Dr. María Ávila-Arcos is Assistant Professor at the International Laboratory for Human Genome Research at the Universidad Nacional Autónoma de México. María earned a PhD in paleogenomics from the University of Copenhagen and trained as a post-doctoral fellow in population genomics and global health at Stanford University. María's previous work included the characterization of ancient genomes with an emphasis on the New World using emerging sequencing technologies and statistical methods. María is currently PI of the Afro-Mexico Genomics Project, a project that aims to characterize the contribution of the TransAtlantic Slave Trade to admixture observed in present-day Mexico. As part of this project, she and her research team have developed culturally-sensitive informed consent protocols and approaches to returning genetic ancestry results to participants. The Ávila-Arcos lab also has projects related to Prehispanic Mexico and Colonialism's impact on genetic diversity over time with possible implications for contemporary disease risk and precision medicine opportunities in populations traditionally underrepresented in genomics.
Recent Publications
- Villanea, FA, Peede, D, Kaufman, EJ, Añorve-Garibay, V, Witt, KE, Villa-Islas, V, Zeloni, R, Marnetto, D, Moorjani, P, Jay, F et al.. The MUC19 gene in Denisovans, Neanderthals, and Modern Humans: An Evolutionary History of Recurrent Introgression and Natural Selection. bioRxiv 2023; : . PubMed PMID:37808839 PubMed Central PMC10557577.
- Tretmanis, JM, Jay, F, Avila-Árcos, MC, Huerta-Sanchez, E. Simulation-based Benchmarking of Ancient Haplotype Inference for Detecting Population Structure. bioRxiv 2023; : . PubMed PMID:37808674 PubMed Central PMC10557694.
- Sandoval-Velasco, M, Jagadeesan, A, Ramos-Madrigal, J, Ávila-Arcos, MC, Fortes-Lima, CA, Watson, J, Johannesdóttir, E, Cruz-Dávalos, DI, Gopalakrishnan, S, Moreno-Mayar, JV et al.. The ancestry and geographical origins of St Helena's liberated Africans. Am J Hum Genet 2023; 110 (10): 1825. PubMed PMID:37802045 PubMed Central PMC10577070.
- Ávila-Arcos, MC, Raghavan, M, Schlebusch, C. Going local with ancient DNA: A review of human histories from regional perspectives. Science 2023; 382 (6666): 53-58. PubMed PMID:37797024 .
- Sandoval-Velasco, M, Jagadeesan, A, Ramos-Madrigal, J, Ávila-Arcos, MC, Fortes-Lima, CA, Watson, J, Johannesdóttir, E, Cruz-Dávalos, DI, Gopalakrishnan, S, Moreno-Mayar, JV et al.. The ancestry and geographical origins of St Helena's liberated Africans. Am J Hum Genet 2023; 110 (9): 1590-1599. PubMed PMID:37683613 PubMed Central PMC10502851.
- COVID-19 Host Genetics Initiative. A second update on mapping the human genetic architecture of COVID-19. Nature 2023; 621 (7977): E7-E26. PubMed PMID:37674002 PubMed Central PMC10482689.
- Tamburrini, C, Dahinten, SL, Saihueque, RRR, Ávila-Arcos, MC, Parolin, ML. Towards an ethical and legal framework in archeogenomics: A local case in the Atlantic coast of central Patagonia. Am J Biol Anthropol 2023; 182 (2): 161-176. PubMed PMID:37525572 .
- Guzmán-Solís, AA, Navarro, MA, Ávila-Arcos, MC, Blanco-Melo, D. A Glimpse into the Past: What Ancient Viral Genomes Reveal About Human History. Annu Rev Virol 2023; 10 (1): 49-75. PubMed PMID:37268008 .
- Villa-Islas, V, Izarraras-Gomez, A, Larena, M, Campos, EMP, Sandoval-Velasco, M, Rodríguez-Rodríguez, JE, Bravo-Lopez, M, Moguel, B, Fregel, R, Garfias-Morales, E et al.. Demographic history and genetic structure in pre-Hispanic Central Mexico. Science 2023; 380 (6645): eadd6142. PubMed PMID:37167382 .
- Ávila-Arcos, MC. The gene variant that helped put Latinxs in the 1000 genomes project. Nat Rev Genet 2022; 23 (12): 712-713. PubMed PMID:36198907 .