
David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System. Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics. MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU). Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area. Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States. And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic). Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time. This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007. More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.
Recent Publications
- Khan, R, Ji, W, Guzman Rivera, J, Madhvi, A, Andrews, T, Richlin, B, Suarez, C, Gaur, S, Hasan, UN, Cuddy, W et al.. A genetically modulated Toll-like receptor-tolerant phenotype in peripheral blood cells of children with multisystem inflammatory syndrome. J Immunol 2025; : . PubMed PMID:40101747 .
- Lavu, M, Hecht, C, Acuna, A, Rizk, A, Kaelber, D, F Kamath, A. Total knee arthroplasty outcomes in patients with a history of radiation therapy. Arch Orthop Trauma Surg 2025; 145 (1): 193. PubMed PMID:40095114 .
- Ashruf, OS, Hundal, J, Mushtaq, A, Kaelber, DC, Anwer, F, Singh, A. Hematologic Cancers Among Patients With Type 2 Diabetes Prescribed GLP-1 Receptor Agonists. JAMA Netw Open 2025; 8 (3): e250802. PubMed PMID:40048168 PubMed Central PMC11886721.
- Kovacevich, A, Dorney, I, Bobak, L, Kaelber, DC, Barnett, BS. Therapeutic Potential of Psychedelics for Treating Anosmia: An Investigation of Online Accounts. J Psychoactive Drugs 2025; : 1-6. PubMed PMID:40022524 .
- Abbass, NJ, Nahlawi, R, Shaia, JK, Allan, KC, Kaelber, DC, Talcott, KE, Singh, RP. The Effect of Semaglutide and GLP-1 RAs on Risk of Nonarteritic Anterior Ischemic Optic Neuropathy. Am J Ophthalmol 2025; 274 : 24-31. PubMed PMID:40015592 .
- Abbass, NJ, Shaia, JK, Shukla, P, Cohen, D, Kaelber, DC, Talcott, KE, Singh, RP. Prevalence of pediatric and adult optic neuritis in the United States from 2016 to 2023. Eye (Lond) 2025; : . PubMed PMID:40011738 .
- Augusto, SN Jr, Issa, R, Vanhentenrijk, S, Kaelber, D, Tang, WHW. Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Amyloidosis With or Without Heart Failure. Am J Med 2025; : . PubMed PMID:39961546 .
- Wiener, JM, Sanghvi, PA, Vlastaris, K, Mroz, T, Belding, J, Kaelber, DC, Olson, T, Francis, KP, Adams, JS, Bernthal, N et al.. GLP-1 Receptor Agonist Medications Alter Outcomes of Spine Surgery: A Study Among Over 15,000 Patients. Spine (Phila Pa 1976) 2025; : . PubMed PMID:39895110 .
- Augusto, SN Jr, Kaelber, D, Tang, WHW. Real-world efficacy of tirzepatide in patients with heart failure without diabetes. Curr Probl Cardiol 2025; 50 (4): 102998. PubMed PMID:39890046 .
- Allan, KC, Joo, JH, Kim, S, Shaia, J, Kaelber, DC, Singh, R, Talcott, KE, Rachitskaya, AV. Glucagon-like Peptide-1 Receptor Agonist Impact on Chronic Ocular Disease Including Age-Related Macular Degeneration. Ophthalmology 2025; : . PubMed PMID:39863057 .