
David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System. Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics. MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU). Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area. Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States. And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic). Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time. This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007. More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.
Recent Publications
- Augusto, SN, Issa, R, Vanhentenrijk, S, Kaelber, D, Tang, WHW. Sodium Glucose Cotransporter 2 inhibitors in Patients with Amyloidosis With or Without Heart Failure. Am J Med 2025; : . PubMed PMID:39961546 .
- Wiener, JM, Sanghvi, PA, Vlastaris, K, Mroz, T, Belding, J, Kaelber, DC, Olson, T, Francis, KP, Adams, JS, Bernthal, N et al.. GLP-1 Receptor Agonist Medications Alter Outcomes of Spine Surgery: A Study Among Over 15,000 Patients. Spine (Phila Pa 1976) 2025; : . PubMed PMID:39895110 .
- Augusto, SN Jr, Kaelber, D, Tang, WHW. Real-world efficacy of tirzepatide in patients with heart failure without diabetes. Curr Probl Cardiol 2025; 50 (4): 102998. PubMed PMID:39890046 .
- Allan, KC, Joo, JH, Kim, S, Shaia, J, Kaelber, DC, Singh, R, Talcott, KE, Rachitskaya, AV. Glucagon-like Peptide-1 Receptor Agonist Impact on Chronic Ocular Disease Including Age-Related Macular Degeneration. Ophthalmology 2025; : . PubMed PMID:39863057 .
- Rao, S, Azuero-Dajud, R, Lorman, V, Landeo-Gutierrez, J, Rhee, KE, Ryu, J, Kim, C, Carmilani, M, Gross, RS, Mohandas, S et al.. Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from the RECOVER Initiative. EClinicalMedicine 2025; 80 : 103042. PubMed PMID:39850015 PubMed Central PMC11753962.
- Sloan, AR, Gordillo, AJ, Kennemer, A, Khorana, AA, Horbinski, C, Kaelber, DC, Cameron, SJ, Lathia, JD. VTE incidence shortens survival in IDH-WT glioblastoma. medRxiv 2025; : . PubMed PMID:39830282 PubMed Central PMC11741497.
- Lavu, MS, Hecht, CJ 2nd, Kaelber, DC, Grammatopoulos, G, Homma, Y, Kamath, AF. Spine-Abductor Syndrome: Novel Associations Between Lumbar Spine Disease and Hip Gluteal Muscle Pathology. J Bone Joint Surg Am 2024; : . PubMed PMID:39813406 .
- Porto, JR, Lavu, MS, Hecht, CJ 2nd, Kaelber, DC, Sculco, PK, Heckmann, ND, Kamath, AF. The Impact of Contemporary Glucagon-like Peptide-1 Receptor Agonists on the Onset, Severity, and Conversion to Arthroplasty in Hip and Knee Osteoarthritis. Orthop J Sports Med 2025; 13 (1): 23259671241297157. PubMed PMID:39811151 PubMed Central PMC11729447.
- Olaker, VR, Fry, S, Terebuh, P, Davis, PB, Tisch, DJ, Xu, R, Miller, MG, Dorney, I, Palchuk, MB, Kaelber, DC et al.. With big data comes big responsibility: Strategies for utilizing aggregated, standardized, de-identified electronic health record data for research. Clin Transl Sci 2025; 18 (1): e70093. PubMed PMID:39740190 PubMed Central PMC11685181.
- Birabaharan, M, Johns, ST, Kaelber, DC, Martin, TCS, Mehta, SR. Atrial Fibrillation after RSV Vaccination Among Older Adults. Clin Infect Dis 2024; : . PubMed PMID:39724318 .