Dr. Perera is an Associate Professor in the Department of Pharmacology and Center for Pharmacogenomics at Northwestern University's Feinberg School of Medicine. With expertise in pharmacokinetics, clinical pharmacology and human genetics, Dr. Perera focuses her research interests on pharmacogenomics in minority populations. Examples of her work include identifying common genetic variants associated with warfarin dose and identifying genomic risk factors for venous thromboembolism, both in African Americans. Dr. Perera anticipates that results from these and other multidisciplinary studies will allow the development of an economically sustainable program in clinical pharmacogenetics, including a consult service. Overall, Dr. Perera's goal is to bring meaningful translation of pharmacogenetics research findings into clinical care, a goal very much consistent with precision medicine.
Recent Publications
- Brochu, HN, Song, K, Zhang, Q, Zeng, Q, Shafi, A, Robinson, M, Humphrey, J, Croy, B, Peavy, L, Perera, M et al.. A program for real-time surveillance of SARS-CoV-2 genetics. Sci Rep 2024; 14 (1): 20249. PubMed PMID:39215120 PubMed Central PMC11364650.
- Edirisinghe, EAHW, Athukorala, BN, Perera, M, Abeywardana, BASD, Sigera, PST, Eranga, P, Theekshana, KD, Boudjelal, M, Ali, R, Peiris, DC et al.. Jellyfish Venom Peptides Targeting Human Potassium Channels Identified through Ligand Screening: Morphometric and Molecular Identification of the Species and Antibiotic Potential. Mar Drugs 2024; 22 (8): . PubMed PMID:39195449 PubMed Central PMC11355547.
- Asiimwe, IG, Blockman, M, Cavallari, LH, Cohen, K, Cupido, C, Dandara, C, Davis, BH, Jacobson, B, Johnson, JA, Lamorde, M et al.. Meta-analysis of genome-wide association studies of stable warfarin dose in patients of African ancestry. Blood Adv 2024; 8 (20): 5248-5261. PubMed PMID:39163621 PubMed Central PMC11493193.
- Mishra, M, Nahlawi, L, Zhong, Y, De, T, Yang, G, Alarcon, C, Perera, MA. LA-GEM: imputation of gene expression with incorporation of Local Ancestry. Pac Symp Biocomput 2024; 29 : 341-358. PubMed PMID:38160291 PubMed Central PMC10764069.
- Yang, G, Alarcon, C, Chanfreau, C, Lee, NH, Friedman, P, Nutescu, E, Tuck, M, O'Brien, T, Gong, L, Klein, TE et al.. Investigation of genomic and transcriptomic risk factors in clopidogrel response in African Americans. medRxiv 2023; : . PubMed PMID:38106031 PubMed Central PMC10723512.
- Yang, G, González, P, Moneró, M, Carrasquillo, K, Renta, JY, Hernandez-Suarez, DF, Botton, MR, Melin, K, Scott, SA, Ruaño, G et al.. Discovery of Ancestry-specific Variants Associated with Clopidogrel Response among Caribbean Hispanics. medRxiv 2023; : . PubMed PMID:37873439 PubMed Central PMC10593031.
- Jayasundara, SL, Algewatta, HR, Jayawardana, S, Perera, M, Peiris, LDC. Molecular Identification and Evolutionary Divergence of the Sri Lankan Sambar Deer, Rusa unicolor (Kerr 1792). Animals (Basel) 2023; 13 (18): . PubMed PMID:37760277 PubMed Central PMC10525601.
- Garofano, K, Rashid, K, Smith, M, Brantner, C, Suwunnakorn, S, Diemert, D, Gordon, O, Horvath, A, Khan, S, Popratiloff, A et al.. Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs. Sci Rep 2023; 13 (1): 2864. PubMed PMID:36806315 PubMed Central PMC9938282.
- Chen, T, O'Donnell, PH, Middlestadt, M, Ruhnke, GW, Danahey, K, van Wijk, XMR, Choksi, A, Knoebel, R, Hartman, S, Yeo, KJ et al.. Implementation of pharmacogenomics into inpatient general medicine. Pharmacogenet Genomics 2023; 33 (2): 19-23. PubMed PMID:36729768 .
- Linder, JE, Allworth, A, Bland, HT, Caraballo, PJ, Chisholm, RL, Clayton, EW, Crosslin, DR, Dikilitas, O, DiVietro, A, Esplin, ED et al.. Returning integrated genomic risk and clinical recommendations: The eMERGE study. Genet Med 2023; 25 (4): 100006. PubMed PMID:36621880 PubMed Central PMC10085845.
