Ignacio Mata, PhD, is Assistant Professor at Cleveland Clinic Lerner College of Medicine. He hold a Bachelor of Science and PhD in Human/Medical Genetics from la Universidad de Oviedo in Asturias, Spain, and he received his PhD in Neurogenetics from Mayo Clinic. Dr. Mata's lab is working towards identifying and understanding the genes that play a role in those diseases that affect the brain (neurological disorders). These include the very well-known Parkinson’s disease (PD), but also other less common disorders such as a form of PD that presents with severe cognitive problems/dementia (PDD) and another type of dementia called Dementia with Lewy Bodies (DLB).
Recent Publications
- Cisterna-Garcia, A, Bustos, BI, Bandres-Ciga, S, Leal, TP, Sarihan, EI, Jok, C, Krainc, D, Mata, IF, Lubbe, SJ, Botia, JA et al.. Genome-wide epistasis analysis reveals significant epistatic signals associated with Parkinson's disease risk. Brain 2024; : . PubMed PMID:39657708 .
- Chaparro-Solano, HM, Rivera Paz, M, Anis, S, Hockings, JK, Kundrick, A, Piccinin, CC, Assaedi, E, Saadatpour, L, Mata, IF. Critical evaluation of the current landscape of pharmacogenomics in Parkinson's disease - What is missing? A systematic review. Parkinsonism Relat Disord 2024; : 107206. PubMed PMID:39551668 .
- Borda, V, Loesch, DP, Guo, B, Laboulaye, R, Veliz-Otani, D, French, JN, Leal, TP, Gogarten, SM, Ikpe, S, Gouveia, MH et al.. Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas. Cell Genom 2024; 4 (11): 100692. PubMed PMID:39486408 PubMed Central PMC11605695.
- Oas, H, Cook, L, Schwantes-An, TH, Walsh, LE, Wills, AM, Mata, IF, Nance, MA, Beck, JC, Naito, A, Marder, K et al.. Participant-reported personal utility of genetic testing for Parkinson's disease and interest in clinical trial participation. NPJ Parkinsons Dis 2024; 10 (1): 202. PubMed PMID:39455611 PubMed Central PMC11511990.
- Salim, A, Biswas, S, Sonneborn, C, Hogue, O, Hennessy, E, Mays, M, Suneja, A, Ahmed, Z, Mata, IF. Efficacy and Tolerability of Anti-CGRP Monoclonal Antibodies in Patients Aged ≥ 65 Years With Daily or Nondaily Migraine. Neurol Clin Pract 2025; 15 (1): e200373. PubMed PMID:39399553 PubMed Central PMC11464238.
- Pereira, GM, Teixeira-Dos-Santos, D, Soares, NM, Marconi, GA, Friedrich, DC, Saffie Awad, P, Santos-Lobato, BL, Brandão, PRP, Noyce, AJ, Marras, C et al.. A systematic review and meta-analysis of the prevalence of Parkinson's disease in lower to upper-middle-income countries. NPJ Parkinsons Dis 2024; 10 (1): 181. PubMed PMID:39349513 PubMed Central PMC11442769.
- Junker, J, Lange, LM, Vollstedt, EJ, Roopnarain, K, Doquenia, MLM, Annuar, AA, Avenali, M, Bardien, S, Bahr, N, Ellis, M et al.. Team Science Approaches to Unravel Monogenic Parkinson's Disease on a Global Scale. Mov Disord 2024; 39 (10): 1868-1873. PubMed PMID:39076159 .
- Cook, L, Verbrugge, J, Schwantes-An, TH, Schulze, J, Foroud, T, Hall, A, Marder, KS, Mata, IF, Mencacci, NE, Nance, MA et al.. Parkinson's disease variant detection and disclosure: PD GENEration, a North American study. Brain 2024; 147 (8): 2668-2679. PubMed PMID:39074992 PubMed Central PMC11292896.
- Lorenzo-Betancor, O, Mehta, S, Ramchandra, J, Mumuney, S, Schumacher-Schuh, AF, Cornejo-Olivas, M, Sarapura-Castro, EH, Torres, L, Inca-Martinez, MA, Mazzetti, P et al.. Parkinson's Disease Gene Screening in Familial Cases from Central and South America. Mov Disord 2024; 39 (10): 1843-1855. PubMed PMID:39051491 PubMed Central PMC11490405.
- Jonson, C, Levine, KS, Lake, J, Hertslet, L, Jones, L, Patel, D, Kim, J, Bandres-Ciga, S, Terry, N, Mata, IF et al.. Assessing the lack of diversity in genetics research across neurodegenerative diseases: A systematic review of the GWAS Catalog and literature. Alzheimers Dement 2024; 20 (8): 5740-5756. PubMed PMID:39030740 PubMed Central PMC11350004.
