Dr. William Stewart is Assistant Professor of Pediatrics at the Ohio State University. Dr. Stewart is also Principal Investigator at The Research Institute of Nationwide Children’s Hospital and a faculty member of the Battelle Center for Mathematical Medicine. Dr. Stewart’s broad research interests include the development of statistical models for quick and efficient analyses of complex datasets, deterministic math models, gene networks, and problems in computational molecular biology.
Recent Publications
- Wu, J, Stewart, WCL, Jayaprakash, C, Das, J. BioNetGMMFit: estimating parameters of a BioNetGen model from time-stamped snapshots of single cells. NPJ Syst Biol Appl 2023; 9 (1): 46. PubMed PMID:37736766 PubMed Central PMC10516955.
- Chen, S, Abou-Khalil, BW, Afawi, Z, Ali, QZ, Amadori, E, Anderson, A, Anderson, J, Andrade, DM, Annesi, G, Arslan, M et al.. Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes. medRxiv 2024; : . PubMed PMID:36865150 PubMed Central PMC9980234.
- Subaran, RL, Stewart, WCL. FREQMAX provides an alternative approach for determining high-resolution allele frequency thresholds in carrier screening. Hum Mutat 2020; 41 (12): 2078-2086. PubMed PMID:33032373 .
- Pathak, S, Stewart, WCL, Burd, CE, Hester, ME, Greenberg, DA. Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice. PLoS One 2020; 15 (6): e0234910. PubMed PMID:32559200 PubMed Central PMC7304595.
- Vieland, VJ, Seok, SC, Stewart, WCL. A new linear regression-like residual for survival analysis, with application to genome wide association studies of time-to-event data. PLoS One 2020; 15 (5): e0232300. PubMed PMID:32365095 PubMed Central PMC7197860.
- Stewart, WCL, Gnona, KM, White, P, Kelly, B, Klebanoff, M, Buhimschi, IA, Nelin, LD. Prediction of short-term neonatal complications in preterm infants using exome-wide genetic variation and gestational age: a pilot study. Pediatr Res 2020; 88 (4): 653-660. PubMed PMID:32023625 PubMed Central PMC7416450.
- Wethington, D, Harder, O, Uppulury, K, Stewart, WCL, Chen, P, King, T, Reynolds, SD, Perelson, AS, Peeples, ME, Niewiesk, S et al.. Mathematical modelling identifies the role of adaptive immunity as a key controller of respiratory syncytial virus in cotton rats. J R Soc Interface 2019; 16 (160): 20190389. PubMed PMID:31771450 PubMed Central PMC6893489.
- Wang, M, Greenberg, DA, Stewart, WCL. In Response: ME2 association analysis in adolescent-onset genetic generalized epilepsy. Epilepsia 2019; 60 (9): 2001-2002. PubMed PMID:31353459 .
- Wang, M, Greenberg, DA, Stewart, WCL. Replication, reanalysis, and gene expression: ME2 and genetic generalized epilepsy. Epilepsia 2019; 60 (3): 539-546. PubMed PMID:30719716 .
- Li, SS, Miller, R, Tumin, D, Stewart, WCL, Tobias, JD, Hayes, D Jr. Lung Allocation Score Thresholds Prioritize Survival After Lung Transplantation. Chest 2019; 156 (1): 64-70. PubMed PMID:30664859 .