Previous Positions
Crawford Post-Doctoral Fellow co-mentored with Dr. Marylyn Ritchie (2009-2011)
Research Faculty, Center for Systems Genomics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University (2011-2014)
Assistant (Investigator I) Professor in the Biomedical and Translational Informatics Program at Geisinger Health System (2015-2019)
Current Position
Genentech (2019-present)
Research Interests
Sarah is a genetic bioinformatician who focuses on high-throughput data analysis and data-mining approaches to studying complex human diseases and traits. Sarah has extensive experience in using both epidemiologic and clinic-based resources to perform phenome-wide association studies (PheWAS) to identify cross-phenotype associations and pleiotropy. Sarah also develops software tools to visualize complex data.
Recent Publications
- Graham, SE, Clarke, SL, Wu, KH, Kanoni, S, Zajac, GJM, Ramdas, S, Surakka, I, Ntalla, I, Vedantam, S, Winkler, TW et al.. Author Correction: The power of genetic diversity in genome-wide association studies of lipids. Nature 2023; 618 (7965): E19-E20. PubMed PMID:37237109 PubMed Central PMC10355188.
- Gorski, M, Rasheed, H, Teumer, A, Thomas, LF, Graham, SE, Sveinbjornsson, G, Winkler, TW, Günther, F, Stark, KJ, Chai, JF et al.. Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. Kidney Int 2022; 102 (3): 624-639. PubMed PMID:35716955 PubMed Central PMC10034922.
- Winkler, TW, Rasheed, H, Teumer, A, Gorski, M, Rowan, BX, Stanzick, KJ, Thomas, LF, Tin, A, Hoppmann, A, Chu, AY et al.. Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. Commun Biol 2022; 5 (1): 580. PubMed PMID:35697829 PubMed Central PMC9192715.
- Piekos, JA, Hellwege, JN, Zhang, Y, Torstenson, ES, Jarvik, GP, Dikilitas, O, Kullo, IJ, Schaid, DJ, Crosslin, DR, Pendergrass, SA et al.. Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid. Hum Genet 2022; 141 (11): 1739-1748. PubMed PMID:35226188 PubMed Central PMC9420161.
- Graham, SE, Clarke, SL, Wu, KH, Kanoni, S, Zajac, GJM, Ramdas, S, Surakka, I, Ntalla, I, Vedantam, S, Winkler, TW et al.. The power of genetic diversity in genome-wide association studies of lipids. Nature 2021; 600 (7890): 675-679. PubMed PMID:34887591 PubMed Central PMC8730582.
- Hall, MA, Wallace, J, Lucas, AM, Bradford, Y, Verma, SS, Müller-Myhsok, B, Passero, K, Zhou, J, McGuigan, J, Jiang, B et al.. Novel EDGE encoding method enhances ability to identify genetic interactions. PLoS Genet 2021; 17 (6): e1009534. PubMed PMID:34086673 PubMed Central PMC8208534.
- Gorski, M, Jung, B, Li, Y, Matias-Garcia, PR, Wuttke, M, Coassin, S, Thio, CHL, Kleber, ME, Winkler, TW, Wanner, V et al.. Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. Kidney Int 2021; 99 (4): 926-939. PubMed PMID:33137338 PubMed Central PMC8010357.
- Palmer, MR, Kim, DS, Crosslin, DR, Stanaway, IB, Rosenthal, EA, Carrell, DS, Cronkite, DJ, Gordon, A, Du, X, Li, YK et al.. Loci identified by a genome-wide association study of carotid artery stenosis in the eMERGE network. Genet Epidemiol 2021; 45 (1): 4-15. PubMed PMID:32964493 PubMed Central PMC7891640.
- Veatch, OJ, Bauer, CR, Keenan, BT, Josyula, NS, Mazzotti, DR, Bagai, K, Malow, BA, Robishaw, JD, Pack, AI, Pendergrass, SA et al.. Characterization of genetic and phenotypic heterogeneity of obstructive sleep apnea using electronic health records. BMC Med Genomics 2020; 13 (1): 105. PubMed PMID:32711518 PubMed Central PMC7382070.
- Cava, W, Bauer, C, Moore, JH, Pendergrass, SA. Interpretation of machine learning predictions for patient outcomes in electronic health records. AMIA Annu Symp Proc 2019; 2019 : 572-581. PubMed PMID:32308851 PubMed Central PMC7153071.
